Daniel Hillard (Robin Williams) is a struggling father who loses his job as a voice actor for cartoons. Daniel's wife, Miranda (Sally Field), has had it with Daniel and wants a divorce. Daniel is denied custody of the children, but is allowed visitations... but seeing his children once a week isn't enough. Daniel disguises himself as "Mrs. Doubtfire," a woman of mature years, a sharp tongue, and an endearing way with the children. In the guise, Daniel charms his way back into the lives of his unsuspecting family.