As a reward for rounding up all 625 experiments, Lilo, Stitch, Jumba, and Pleakley have been placed around the galaxy in a spot where each of them thinks they truly belong. Their lives are all shook up when the dastardly Dr. Hamsterviel breaks out of prison and forces Jumba to create a new experiment -- Leroy, the evil twin of Stitch. Hamsterviel soon clones the nasty little creature to form his own mischievous army.